Examples of our work

Here are a few examples of our services. More information and price indications on request.

Bioinformatic analysis

EXAMPLE. A client was interested in patterns observed in the ORF distribution of a particular micro-organism and would like to know the biological relevance of the observations. MMGC analysed the patterns  and correlated to the biological properties of the organism. This opened a new field of computer-based research.

EXAMPLE. A client had performed subtractive hybridization with two strains of one bacterial species. The resulting clones had been partially sequenced. Most gene fragmens had no or only weak hits in BLAST. A thorough analysis was performed by MMGC to identify the top 10 candidates to focus the wet-lab research.This resulted in a fast and resource-efficient breakthrough.

EXAMPLE. A client wanted to identify particular gene combinations in a bacterial genome responsible for a particular, complex phenotype. Total bacterial genome comparison was performed with PSI-BLAST and rthe outcome was elated to known phenotypes to deduce this complex information to workable hypotheses.

EXAMPLE. A client was working on a particular antibiotic resistant gene and ordered a literature review. This was extended to a review of available sequences. Phylogenetic anaysis, performed at MMGC, resulted in a new mechanism of spread of this resistance gene, which opened a new field of laboratory research.

Press release:
Hepatitis A was once an insect virus

We are proud to announce our latest publication, in which we performed a thorough analysis of Hepatitis A virus and discovered that this virus most likely had an ancestor virus replicating in insects. The work was initiated by MMGC in collaboration with colleagues from UAMS
For a Press release click here >
The publication is open source and can be found here.

Latest News

Press release: Hepatitis A was once an insect virus

We are proud to announce our latest publication, in which we performed a thorough analysis of Hepatitis A virus and discovered that this virus most likely had an ancestor virus replicating in insects. The work was initiated by MMGC in collaboration with colleagues from UAMS

For a Press release click here

The publication is open source and can be found here

Book recommendation

Bacteria: The Benign, the Bad, and the BeautifulBacteria:
The Benign,
the Bad, and
the Beautiful

Dr. Trudy Wassenaar

 

Publisher's info